EPA’s Science Advisory Panel met on July 30-August 2, 2013, to review “Weight-of-Evidence: Evaluating Results of EDSP Tier 1 Screening.” The SAP has released the minutes of this meeting. They criticized EPA’s Tier 1 Amphibian Metamorphosis Assay on several grounds, including the following:
“The concentrations of Chemical S achieved in the aquarium water in the AMA were below the targeted nominal concentrations, and there was large variability in the measured concentrations. For these reasons the Panel disagreed with the Agency’s conclusion that the exposure was reasonably quantified. Because of the low solubility and high variability in the measured concentrations of Chemical S, and a lack of information on how the measured concentrations of Chemical S compare to expected environmental exposures, the Panel concluded that the results do not enable reviewers to determine responses.”
This is the third SAP to criticize EPA’s AMA.
Click here for Weight of Evidence SAP minutes.