SAB Critically Reviews EPA’s Comptox

EPA’s Science Advisory Board met on March 7-8, 2013, to review several issues including EPA “Risk Assessments—Use of Computational Toxicology.” EPA hopes to use CompTox in several contexts, including the Agency’s Endocrine Disruptor Screening Program. Given its proposed EDSP use, and the EPA Science Advisory Panel’s continuing review of CompTox, SAB Member Dr. Elaine Faustman pointed out that “[t]he review highlights in several contexts the significance of the early use of the CompTox data for screening dispersants in the Gulf however it is silent of the very large exercise of screening for endocrine disruption that is occurring as a part of the EPA endocrine screening program. Shouldn’t the review applaud EPA’s approach to emphasize the importance of such evaluations of Comp Tox results for current EPA needs?”

EDSP SAP Meets in May

There will be a 4-day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel to consider and review the Endocrine Disruptor Screening Program Tier 1 Screening Assays and Battery Performance. The meeting will be held on May 21 – 24, 2013, from approximately 9 a.m. to 5 p.m., at the Environmental Protection Agency,
Conference Center, Lobby Level, One Potomac Yard (South Bldg.), 2777 S. Crystal Dr.,
Arlington, VA 22202. EPA encourages that written comments be submitted by May
7, 2013, and requests for oral comments be submitted by May 14, 2013. However,
written comments and requests to make oral comments may be submitted until the date of
the meeting. Anyone submitting written comments after May 7, 2013 should contact
Fred Jenkins Jr., DFO, Office of Science Coordination and Policy (7201M), Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460-0001; telephone number: (202) 564-3327; fax number: (202) 564-8382; email address:

SAB Recommends that EPA Develop Data Use Guidelines for CompTox

On March 7, 2013, at 1:15 p.m., EPA’s Science Advisory Board will review the draft SAB Report “SAB Advice (1/29/13 Draft) on Advancing the Application of CompTox Research for Human Health Risk Assessment.” A copy of this draft report is available here.

This draft report includes several recommendations, one of which is that “EPA should develop data use guidelines for information generated by CompTox, including ExpoCast, for the various purposes to which it is intended.”

EPA SAB Meets on CompTox Reports

The Environmental Protection Agency’s Science Advisory Board will meet publicly on March 7, 2013, from 10:30 a.m. to 6:00 p.m. and Friday, March 8, 2013, from 8:00 a.m. to 1:00 p.m. The SAB will perform a number of reviews at this meeting. One of them is a quality review of three draft SAB reports on the use of computational toxicology to advance risk Assessment. The SAB meeting will be held at the Washington Marriott, 1221 22nd Street NW, Washington, DC, 20037.

EDSP Plans on Three More EDSP SAPs

On January 29-31, the FIFRA Science Advisory Panel reviewed EPA’s current efforts to prioritize the universe of Endocrine Disruptor Screening Program chemicals using computational toxicology tools. At this SAP meeting, EPA representatives stated that the Agency intends to convene three more SAPs in 2013 to review EDSP issues. According to EPA, these three additional SAPs will

● the first additional SAP will review some “operational aspects” of the current EDSP tier 1 tests;

● the second additional SAP will review the validation status of the EDSP Tier 2 tests that EPA is developing; and

NAS/NRC Hopes to Publish FIFRA/ESA Consultations Final Report in February 2013

NAS/NRC representatives have informed CRE that they now hope to publish the report in NAS/NRC’s review of Ecological Risk Assessment under FIFRA and ESA in February 2013.  The NAS/NRC Review Committee intends to publish its report in final form, without allowing public comment on a draft report.  The Committee’s website for this project is available online


EPA Proposes New Rules for Minimum Risk Pesticides

EPA has published a Federal Register notice soliciting public comment on the Agency’s proposed new regulations on the active and inert ingredients permitted in products eligible for the exemption from regulation for minimum risk pesticides. EPA proposes adding specific chemical identifiers that would make it clearer to manufacturers; the public; and Federal, state, and tribal inspectors which ingredients are permitted in minimum risk pesticide products. EPA is also proposing to modify the label requirements in the exemption to require the use of specific common chemical names in lists of ingredients on minimum risk pesticide product labels, and to require producer contact information on the label.  EPA must receive any public comments on these proposals on or before April 1, 2013.

Enviros Oppose Industry Intervention in ESA Pesticides Mega Suit

Environmental NGOs are suing EPA, asking a California federal district court to essentially take over EPA’s pesticide program because EPA allegedly failed to meet all its pesticide obligations under the Endangered Species Act. Several industry Interveners have moved to intervene in the case. The Interveners include CropLife America and the American Chemistry Council. The court has not yet granted them full participation in the case.


The NGO plaintiffs have filed an Opposition to the industry motion to intervene.  Their Opposition makes the following arguments:



Enviros Respond to EPA’s Motion to Dismiss Mega-Pesticides Case

Environmental NGOs are suing EPA, basically asking a California federal district court to take over EPA’s pesticide program because EPA allegedly failed to meet all its ESA consultation obligations under the Endangered Species Act. EPA has filed a motion to dismiss the Plaintiffs’ complaint in the case. The Plaintiffs have filed their opposition to EPA’s motion to dismiss.  The Plaintiffs’ opposition makes the following arguments:


I.  Defendants’ Motions Improperly Elevate FIFRA above the ESA


II. EPA’s Continuing Authority over Pesticide Registrations is Ongoing Agency Action Subject to the ESA’s Consultation Requirement


EPA Seeks Comment on Proposed Pesticide Label Changes

EPA has published Federal Register notice seeking public comment on a draft Pesticide Registration Notice.  This draft PR Notice describes appropriate label language for fungicides and fungistats, and for products used for mold remediation, on nonporous and porous surfaces, for residual activity, for mold prevention, and in heating, ventilation, air conditioning and refrigeration systems. These recommended label changes are designed to improve protection of public health through proper use of mold-related pesticides. Comments on this draft PR Notice must be received on or before February 11, 2013.

  • Click here to read EPA’s Federal Register notice