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®: CRE Regulatory Action of the Week

NIEHS/NTP Seeks Thousands of Genes for New Screening Program
The National Institute of Environmental Health Sciences/National Toxicology Program requests the nomination and prioritization of environmentally responsive genes from humans and other species for use in screening large numbers of substances using toxicogenomic technologies. The goal of this program is to generate a minimum list of 1000 genes for each species that would provide the maximal toxicogenomic information on (1) effects that reflect general cellular responses, independent of cell type or species, and (2) gene expression changes that are specific by organ and/or cell type. The NIEHS/NTP also seeks recommendations on criteria to use for prioritizing the genes in order to identify those potentially most useful in a screening paradigm. The deadline for receipt of information is August 23, 2013.

  • Click here to read Federal Register notice seeking information